The blog

Notes on living well, without making it a full-time job.

Each post takes one study, report or headline and asks what it actually shows. Every one ends with the subtraction: one thing you can stop doing, buying or worrying about.

Latest post · October 23, 2026

Weekend reading: a Stanford trialist's sensible book about food, and why we name the sensible ones

Weekend Reading · Real Food

This site has a rule: we do not name the people we think are selling you complexity; we describe the pattern and let you recognize it. The rule has a corollary we use less often than we should: we do name the people getting it right.

By Ben Dubin and Dr. Loree Pinnavaia · 3 min readRead the post →

2026

  1. Industry · Purpose

    Two reports in two days: one counts the people, one counts the market

    Yesterday the Milken Institute published The Future of Aging and Longevity: A Decade of Progress, A Decade to Act, a collection of essays and interviews from more than fifty contributors — foundations, universities, AARP, Meals on Wheels, the MIT AgeLab, the Stanford Center on…

    4 min read
  2. Mouse Dish or Human?

    An 80-year-old's blood cells were made 60 years 'younger' in a dish. A dish result is a dish result.

    Researchers at the University of Bonn announced today, in Aging Cell, that they had converted blood-cell precursors from an 80-year-old donor directly into neural stem cells and watched the cells' epigenetic age — the DNA-methylation clock reading — fall to under 20 years over…

    4 min read
  3. Follow the Money · Clinical

    Nonprofit hospitals are selling longevity packages from $5,500. Here is what in them is free.

    STAT published the first part today of a series on a trend we have watched arrive: cash-pay longevity clinics inside nonprofit academic hospitals, naming Northwestern, Weill Cornell and the Mayo Clinic.

    5 min read
  4. Follow the Money · Industry

    The aging industry's annual self-portrait convenes at Harvard today. Read the sponsor list.

    The Aging Research and Drug Discovery meeting — the largest conference in longevity biotechnology, now in its thirteenth year and in Boston for the first time — opens today at Harvard and runs through Friday.

    4 min read
  5. Follow the Money · Real Food

    91% of the papers criticizing the ultra-processed-food category had an industry-tied author

    On Tuesday we said to watch who makes the argument against the ultra-processed-food evidence, and who paid for the making. A systematic review in the American Journal of Public Health, described this week by the Oregon Research Institute, has done the counting.

    4 min read
  6. Connection · One Chart

    40% of Americans report moderate to severe loneliness. The barrier they name is time.

    The second annual Social Connection in America survey, run by RAND and The Connection Institute with Julianne Holt-Lunstad — the author of the 148-study meta-analysis this site cites more than any other — as its scientific lead, was released this morning.

    4 min read
  7. Real Food · Evidence

    8.8 million people, 51 cohorts, one direction. And what 'associated' means in numbers you can use.

    The largest pooled analysis of ultra-processed food and chronic disease to date was released today in Family Medicine and Community Health: 51 prospective cohorts, 8,819,894 adults, followed for two to thirty-two years across four continents.

    5 min read
  8. Sleep · Evidence

    The sleep science honored last night took 28 years. The sleep hack took a video.

    Last night in New York the Lasker Foundation presented its basic-research award, often called America's Nobel, to Emmanuel Mignot of Stanford and Masashi Yanagisawa of the University of Tsukuba for identifying orexin, the brain peptide that keeps us awake.

    4 min read
  9. Sleep · Evidence

    More REM, less disease: a 95,559-person study, and why your ring's REM number is still not this

    A study published today inPLOS Medicine is the largest look yet at sleep stages and disease. Researchers in Beijing took seven days of wrist-accelerometer data from 95,559 UK Biobank participants, estimated REM, deep sleep, wakefulness and irregularity with a machine-learning model…

    5 min read
  10. Real Food · Clinical

    Texas wrote its own dietary guidelines today. Six lines, one sentence we'd keep, and a rule for medical schools.

    The Texas Nutrition Advisory Committee, created by a 2025 state law, published the first Dietary Guidelines for Texans today. There are six: fill half your plate with vegetables and fruit; eat three or more servings of healthy proteins a day; include healthy fats; eat foods for…

    4 min read
  11. Movement · Evidence

    Fewer steps, taken faster: a 103,684-person study says pace counts too

    Last July the largest review of step counts put the point of diminishing returns around 7,000 a day. A study published today in the British Journal of Sports Medicine adds the other variable.

    4 min read
  12. Sleep · Clinical

    GLP-1 drugs help sleep apnea. The machine still beats them, and most people won't wear it.

    A review published today in JAMA Otolaryngology–Head & Neck Surgery does the sorting that sleep-apnea patients have needed since tirzepatide was approved for the condition in December 2024.

    4 min read
  13. Mouse Dish or Human?

    Mouse, dish or human? Semaglutide extended lifespan in old female mice by 92 days.

    A paper in Nature today, with a same-day release from the National Institutes of Health, reports that semaglutide — the molecule in Wegovy — given to female mice from 20 months of age extended their median lifespan from 742 days to 834, about 12%.

    4 min read
  14. Evidence · Industry

    The aging clocks respond to interventions. The authors say that is not the same as being right.

    Four days after a study explained why epigenetic clocks disagree, a second one — in Nature Medicine today, described by Yale — asks whether they move.

    4 min read
  15. Evidence · Industry

    Two biological-age tests, two answers. A study of 3,227 people explains why.

    Patients bring us two biological-age results from two companies and ask which is right. A study from the University of Southern California, published in npj Aging and described by the university last week, offers the best answer so far: they are measuring different things.

    4 min read
  16. Psychology of Optimization · Evidence

    A scientist ran a longevity study on one person: himself. Read the limitations section first.

    A university in Singapore announced today that one of its professors had, in a study published yesterday in PLOS ONE, reduced his estimated biological age from 47 to about 32.

    4 min read
  17. Industry · Evidence

    Twenty finalists, ten million dollars, and a yardstick that hasn't moved

    XPRIZE named twenty finalists today in its $101 million Healthspan competition, ten of them receiving $1 million milestone awards. When we wrote about the forty semifinalists in May of last year, we said the thing to watch was the yardstick: to win, a team has to restore muscle…

    4 min read
  18. Sleep · Evidence

    A sleep drug was approved today on trial data. Note what the sleep aisle has never had to show.

    The FDA approved oveporexton today, the first drug that works by switching on the brain's orexin system — the wakefulness signal that is missing in people with narcolepsy type 1, a condition affecting an estimated 120,000 Americans.

    4 min read
  19. Follow the Money

    $450 million to pay for marketing, repaid by members: the blood-panel funnel gets its own fund

    Function Health, the 160-test membership we wrote about in November, announced $450 million today from a General Catalyst vehicle called the Customer Value Fund.

    4 min read
  20. Connection · One Chart

    Another country counts: half of Australians report some form of social disconnection

    Ending Loneliness Together, the Australian research coalition led from the University of Sydney, released its State of the Nation report today: a nationally weighted survey of 4,001 people aged 12 to 95, fielded in January and February.

    3 min read
  21. Evidence · Mouse Dish or Human?

    A model says the ceiling on human life is 146 to 194 years. A model is a model.

    A paper published last month in npj Aging is making the rounds this week under headlines about living to 190. The authors built a mathematical model in which the body is a chain of critical organs, each losing cells to lethal mutations over time, and asked how long a person would…

    4 min read
  22. Follow the Money

    The full-body scan comes to Manhattan with $700 million. The business is the second scan.

    Neko Health, the Stockholm company co-founded by Spotify's founder, announced a $700 million Series C today, led by Lightspeed, ahead of a US launch beginning in New York later this year.

    4 min read
  23. Purpose · Evidence

    Purpose in life and dying: the largest analysis yet, 488,765 people, and the honest size of the effect

    A meta-analysis published today inPsychological Medicine, open access, pools 25 samples — eight large national cohorts with individual-level data plus 17 published studies — totaling 488,765 people followed for up to 32 years, with 48,928 deaths.

    4 min read
  24. Follow the Money · Industry

    The FDA closed the WHOOP blood-pressure letter. The two words that matter are 'as modified.'

    Eleven months after it told WHOOP that an estimated-blood-pressure feature was on the wrong side of the line between wellness and medicine, the FDA has closed the matter.

    4 min read
  25. Movement · Evidence

    Ninety minutes a week of strength training was the sweet spot in 147,374 people. More didn't help; none was worse.

    The largest long-term study of strength training and death was published today in the British Journal of Sports Medicine: 147,374 health professionals in three American cohorts, followed for up to thirty years, with 35,798 deaths and exercise reported every two years.

    4 min read
  26. Evidence · Clinical

    The first person has been dosed with a reprogramming therapy. Phase 1 means safety, not benefit.

    Life Biosciences announced today that the first participant has been dosed in the Phase 1 trial of ER-100, the partial epigenetic reprogramming therapy whose trial clearance we covered in January.

    4 min read
  27. Real Food · Evidence

    Three scientists say the trials don't prove processing itself is the problem. Here is the argument without the spin — theirs or ours.

    A Perspective in Science today, by nutrition researchers at Copenhagen, Wageningen and Liverpool (DOI 10.1126/science.aef3495), reviews the five controlled feeding trials that compare ultra-processed and minimally processed diets and concludes that they provide weak support for an…

    5 min read
  28. Follow the Money · Industry

    A reprogramming company's valuation tripled in a year. What changed is a date.

    NewLimit, the epigenetic-reprogramming company we wrote about last October, announced a $435 million Series C today, led by Founders Fund, with Eli Lilly's venture arm returning alongside a long list of new and existing investors.

    4 min read
  29. Follow the Money · Industry

    A $1.8 billion valuation and no human efficacy data. Here is how the math works.

    Retro Biosciences, the longevity company founded with roughly $180 million from the chief executive of OpenAI and with the stated goal of adding ten years to healthy human lifespan, announced today an initial close of its next financing at a pre-money valuation of $1.8 billion, led…

    4 min read
  30. Follow the Money

    The ring filed to go public. The prospectus will be the most honest document the wearable industry has produced.

    Oura announced today that it has confidentially submitted a draft registration statement to the Securities and Exchange Commission for an initial public offering.

    4 min read
  31. Sleep · Evidence

    Too little sleep and too much both age every organ system. The sweet spot is boring.

    A paper in Nature today, described by Columbia University, takes the biological-age idea the consumer industry sells one number at a time and runs it properly: 23 aging clocks built from brain and body imaging, blood proteins and metabolites, spanning 17 organ systems, in UK Biobank…

    4 min read
  32. Connection · One Chart

    One in five Americans was lonely 'a lot of the day yesterday.' That number belongs on every health dashboard.

    Gallup's latest well-being report, published today, is headlined by depression — 19.1% of US adults say they currently have or are being treated for it, roughly 51 million people, nearly double the 2015 figure — but the line we watch is the one underneath.

    4 min read
  33. One Chart · Follow the Money

    One chart: twelve deals took 59% of the quarter's health money. The band was the biggest.

    Rock Health's first-quarter tally, out today, counts $4.0 billion of venture money into US digital health across 110 deals, up from $3.0 billion across 122 deals a year ago.

    3 min read
  34. Follow the Money

    Investors just paid about $4,000 per wrist for a $199-a-year band. Read the arithmetic.

    WHOOP, the fitness-band company that received an FDA warning letter over a blood-pressure feature last July, has raised $575 million at a valuation of $10.1 billion, led by Collaborative Fund.

    4 min read
  35. Evidence · Real Food

    A preprint says ultra-processed food raises frailty risk 43%. Here is how to read a preprint.

    A paper posted today on medRxiv pools ten observational studies of ultra-processed food and frailty in older adults — 105,000 participants across the United States, Spain, Italy, Australia, Singapore, Iran and China — and reports that higher intake was associated with 43% higher odds of frailty.

    4 min read
  36. Connection · Purpose

    Loneliness shortens life mostly by taking your reasons. A new study puts the share at 88%.

    Connection and purpose are two of the five fundamentals, and a paper in the March issue of Social Science & Medicine suggests they are closer to one fundamental wearing two hats.

    4 min read
  37. Sleep · Evidence

    If you want to know whether one hour of sleep matters, look at Monday

    Clocks moved forward at 2 a.m. this morning and most of the country lost an hour of sleep at once. You cannot run a randomized trial that takes an hour of sleep from three hundred million people, but twice a year a government does it for free, and researchers have been reading the…

    3 min read
  38. Follow the Money · Clinical

    The FDA warned 30 telehealth companies about GLP-1 ads. The word at issue is 'same.'

    The FDA announced today that it has sent warning letters to 30 telehealth companies over the marketing of compounded GLP-1 drugs — versions of semaglutide and tirzepatide made by compounding pharmacies rather than the manufacturers.

    4 min read
  39. Real Food

    'Eat real food' is now a federal slogan. The sentence is right. The test is what follows it.

    Last night in Austin the Secretary of Health and Human Services headlined an "Eat Real Food" rally of more than 600 people, and this morning served broccoli to third-graders at an elementary school on a tour promoting the new Dietary Guidelines.

    4 min read
  40. Connection

    The oldest study of happiness has one finding, and it isn't about romance

    Today is the one day a year the country agrees that a relationship is worth money. The longest-running study of adult life ever conducted agrees too, but not about which relationship.

    3 min read
  41. Follow the Money · Evidence

    The first longevity drug may be for dogs. That's the honest path, and here's why.

    Loyal, the company developing lifespan-extension drugs for dogs, announced a $100 million Series C today, bringing its total raised past $250 million.

    4 min read
  42. Evidence · Mouse Dish or Human?

    The first reprogramming therapy is cleared for a human trial. 'Cleared to test' and 'shown to work' are different sentences.

    Life Biosciences announced today that the FDA has cleared its investigational new drug application for ER-100, which the company describes as the first cellular rejuvenation therapy using epigenetic reprogramming to be allowed into human trials.

    4 min read
  43. Follow the Money · Real Food

    How a diet becomes a subscription: a sovereign fund buys into the five-day fast

    L-Nutra, the Los Angeles company behind ProLon — a five-day kit of soups, bars and drink mixes designed to mimic a fast — announced today a $36.5 million investment led by Mubadala, Abu Dhabi's sovereign wealth fund, bringing its Series D to $83.5 million.

    4 min read
  44. Evidence · The Fundamentals

    Two papers in a week priced the fundamentals in years. Here is the receipt.

    Two large studies from a University of Sydney team landed this week, and together they are the closest thing we have to a price list for the fundamentals.

    5 min read
  45. Real Food

    The new Dietary Guidelines say 'eat real food.' Here is what is in the ten pages, and what isn't.

    The Departments of Health and Human Services and Agriculture released the 2025–2030 Dietary Guidelines for Americans today. The document is ten pages long; the previous edition ran 164.

    5 min read
  46. Follow the Money · Clinical

    A prescription drug now costs what a longevity subscription does. Compare what you get.

    The pill version of Wegovy, approved two weeks ago, went on sale today at more than 70,000 US pharmacies, including CVS and Costco, and through telehealth companies.

    4 min read

2025

  1. Follow the Money · Industry

    An AI drug company that promises 'productive longevity' listed today. Its lead drug is for lungs, not aging.

    Insilico Medicine began trading on the Hong Kong Stock Exchange this morning under the code 3696, raising about HK$2.28 billion — roughly US$290 million — in what the company calls the largest Hong Kong biotech IPO of the year.

    4 min read
  2. Clinical · Evidence

    A weight-loss pill with trial data. The longevity aisle should take notes.

    The FDA approved today a once-daily pill form of semaglutide, the GLP-1 drug sold as Wegovy, for chronic weight management. In the trial that supported it, 307 adults took the pill or a placebo for 64 weeks; those on the drug lost on average 13.6% of body weight against 2.4% on…

    4 min read
  3. Evidence · Connection

    The Blue Zones researchers answered. Here is what the reply settles, and what it can't.

    Fifteen months ago we wrote about the Ig Nobel Prize awarded to a demographer whose work argues that many of the world's claimed oldest people are the product of missing birth certificates and pension fraud, and that the Blue Zones might be artifacts of bad records.

    4 min read
  4. Follow the Money

    160 biomarkers for $365. The reference range is where the money is.

    Function Health, the direct-to-consumer lab-testing company, announced today a $298 million Series B at a $2.5 billion valuation, bringing its total raised to about $350 million.

    4 min read
  5. Clinical · Sex Differences

    The black box came off hormone therapy today. A 22-year label, built on 63-year-old participants.

    The FDA announced today that it will remove the boxed warnings on menopausal hormone therapies for cardiovascular disease, breast cancer and probable dementia.

    4 min read
  6. Sleep · Evidence

    Melatonin, heart failure, and the number the headline won't give you

    The American Heart Association released a study today that will be summarized tomorrow as "melatonin linked to heart failure," and the summary will be both accurate and misleading.

    4 min read
  7. Sleep · The Subtraction

    You got an hour back at 2 a.m. this morning. Here is the only sleep product that has ever worked.

    Clocks fell back an hour at 2 a.m. this morning, and most of the country got the one sleep intervention with no subscription, no sensor and no side effects: more time in bed.

    3 min read
  8. Follow the Money · Mouse Dish or Human?

    One of the world's largest drugmakers just bought into cellular reprogramming. Read what 'clinical' means here.

    NewLimit, the San Francisco company working on epigenetic reprogramming — resetting the chemical marks that tell a cell how old to act — announced today an additional $45 million from Eli Lilly, Duke University's endowment, Section 32 and existing investors, at a $1.62 billion…

    4 min read
  9. Follow the Money

    The ring is now worth $11 billion and sells blood tests. We said this would happen.

    Oura, the Finnish smart-ring maker, announced today a $900 million round led by Fidelity at a valuation of about $11 billion — roughly double where it raised ten months ago.

    4 min read
  10. Real Food · Follow the Money

    Everything has protein in it now. The thing being sold is the word.

    Protein ice cream. Protein soda. Protein water. Protein pancakes, chips, popcorn, candy. Semafor reports today that sales of products marketed as protein-rich rose 4.8% year over year through March, and that the food industry is reformulating whole aisles around a single nutrient.

    4 min read
  11. Industry

    Apple's watch got cleared for what WHOOP got a warning letter for. The difference is the paperwork, and the design.

    The FDA cleared Apple's hypertension notifications last night, three days after the company announced them. The feature runs passively on the watch's optical heart sensor, looks for patterns consistent with chronic high blood pressure over thirty-day windows, and sends a notification…

    4 min read
  12. Real Food · Clinical

    Doctors get about 19 hours of nutrition training. Patients get podcasts.

    The Department of Health and Human Services and the Department of Education asked medical schools today to strengthen nutrition education across pre-med, medical school and residency, and to report their commitments within two weeks.

    4 min read
  13. Supplements · Evidence

    The second shoe drops on taurine: no link to age, muscle, strength or function in people

    In June, Science reported that circulating taurine does not decline with age in humans, monkeys or mice, undercutting the premise of a supplement boom that started with a 2023 mouse paper.

    3 min read
  14. Real Food · Evidence

    The American Heart Association drew the line on ultra-processed food. Here is where it is.

    The American Heart Association published a science advisory today in Circulation on ultra-processed foods — industrial formulations built from refined ingredients and additives, the category the Nova classification calls group four.

    4 min read
  15. Movement

    12,500 athletes over fifty are in Des Moines this week. None of them are optimizing.

    The National Senior Games open today in Des Moines, Iowa, and run through August 4: more than 12,500 registered athletes, all at least fifty years old, competing in 25 sports from track and swimming to pickleball and powerlifting.

    4 min read
  16. Movement · Evidence

    10,000 steps was a marketing number. 7,000 is the data.

    The 10,000-step target began life as the name of a Japanese pedometer in the 1960s — manpo-kei, the ten-thousand-step meter — and has survived sixty years on the strength of being a round number.

    4 min read
  17. Clinical · Sex Differences

    An FDA panel wants the scariest warning on hormone therapy gone. The 2002 study behind it was about different women.

    An expert panel convened by the FDA commissioner urged the agency today to remove the boxed warning — the agency's most severe label — from menopausal hormone therapies, beginning with low-dose vaginal estrogen.

    4 min read
  18. Follow the Money · Industry

    The FDA just told a wearable where wellness ends. Blood pressure is on the other side.

    The FDA has sent WHOOP, the Boston fitness-band company, a warning letter dated July 14 over Blood Pressure Insights, a feature that gives wearers a daily estimated blood-pressure range on a green-yellow-orange gauge.

    4 min read
  19. Connection

    871,000 deaths a year: the WHO put a number on loneliness

    The WHO Commission on Social Connection, after a three-year investigation, reported today that about one person in six worldwide is affected by loneliness, and that over 2014 to 2019 loneliness was associated with an estimated 871,000 deaths a year — roughly a hundred an hour.

    4 min read
  20. Supplements · Evidence

    Taurine doesn't decline with age after all. Two years, one supplement boom, one correction.

    In June 2023, Science published a paper reporting that circulating taurine — an amino acid, best known as an energy-drink ingredient — falls with age, and that supplementing it extended lifespan in worms and mice and improved health markers in monkeys.

    4 min read
  21. Evidence

    A federal health report cited studies that don't exist. Here is how to check a citation in ninety seconds.

    On May 22 the federal Make America Healthy Again Commission released a 78-page report on childhood chronic disease, attributing rising rates to ultra-processed food, chemical exposures, lifestyle and over-prescribing.

    4 min read
  22. Connection

    The World Health Assembly just made loneliness a health priority. It took a vote to say the obvious.

    This week in Geneva the World Health Assembly adopted its first resolution on social connection, co-sponsored by Spain and Chile. It urges member states to build strategies for meaningful social connection into national health policy, to collect data on loneliness and isolation, to…

    4 min read
  23. Sleep · Evidence

    Mouth taping got its review: ten studies, 213 people and a warning

    Taping your mouth shut at night is a social-media sleep hack with millions of views and, as of today, a systematic review in PLOS ONE. Ear, nose and throat researchers at Western University in Ontario found ten studies with a combined 213 patients.

    3 min read
  24. Industry · Evidence

    A $101 million prize for restoring ten years of function. Watch the yardstick, not the money.

    XPRIZE named forty semifinalists today in its $101 million Healthspan competition, chosen from more than 600 teams in 58 countries. Each gets $250,000 to run a trial.

    4 min read
  25. Real Food · Evidence

    Fasting beat calorie counting by 2.9 kilograms. Look at what both groups actually did.

    A randomized trial published today in the Annals of Internal Medicine will be reported as a win for intermittent fasting, and in a narrow sense it is.

    4 min read
  26. Connection · Psychology

    The chatbot's maker studied loneliness. Its heaviest users had more of it.

    OpenAI and the MIT Media Lab released two studies of what ChatGPT does to the people who use it most. One analyzed nearly 40 million interactions automatically; the other was a four-week randomized trial of 1,000 people.

    4 min read
  27. Sleep

    The hour you lost this morning, and where it comes from

    At 2 a.m. this morning, most of the United States moved its clocks forward an hour. Nobody slept it. The hour was taken from the night, by statute, from roughly 330 million people at once, and tomorrow morning is the one day a year the entire country wakes up jet-lagged in the same direction.

    3 min read
  28. Follow the Money

    Whole-body MRI raised $120 million. The radiologists' own college says don't.

    Prenuvo, the whole-body MRI company, announced today a $120 million Series B co-led by Forerunner Ventures and Left Lane Capital, with investors including Cindy Crawford, Anne Wojcicki and Eric Schmidt.

    4 min read
  29. Follow the Money

    The biggest checkbook in aging science belongs to a government. That changes the questions.

    The second Global Healthspan Summit wraps up today in Riyadh. Its host, the Hevolution Foundation, was created by Saudi royal decree, describes an annual budget of up to $1 billion, and says it has committed $400 million to aging research over the past three years, which makes it the…

    4 min read
  30. Evidence

    The cold plunge got its meta-analysis. The benefits last about twelve hours.

    Researchers at the University of South Australia published this week in PLOS ONE the first systematic review and meta-analysis of cold-water immersion in healthy adults: eleven studies, 3,177 participants, cold showers, ice baths and plunges with water at chest level or higher for at…

    4 min read
  31. Follow the Money

    A £299 full-body scan just raised $260 million. Here is what a scan can and cannot tell you.

    Neko Health, the Stockholm company co-founded by Spotify's Daniel Ek, announced today a $260 million Series B led by Lightspeed Venture Partners, reportedly valuing it at about $1.8 billion.

    4 min read
  32. Real Food · Evidence

    The FDA banned a red dye today. The reason is in the fine print.

    The FDA announced today that it is revoking the authorization for FD&C Red No. 3 in food and ingested drugs. The dye is the bright cherry red in candy, frosting, maraschino cherries and some medicines.

    4 min read
  33. Connection · Purpose

    The Surgeon General's last prescription has no drug in it

    Vivek Murthy, leaving office this month after two terms as US Surgeon General, released a document today he calls a Parting Prescription for America. It has no dosing table.

    4 min read
  34. Real Food · Evidence

    Two reports, seventeen days apart, two answers on alcohol. Both are right.

    The US Surgeon General issued an advisory today calling alcohol a leading preventable cause of cancer — about 100,000 cases and 20,000 deaths a year in the United States, across at least seven cancer types — and asked Congress to put a cancer warning on the label.

    5 min read

2024

  1. Follow the Money

    A ring is worth $5.2 billion. The thing it measures is free.

    Oura, the Finnish company behind the smart ring, announced today that it has closed a $200 million Series D at a $5.2 billion valuation, with Fidelity and the glucose-sensor maker Dexcom participating.

    4 min read
  2. Real Food · Evidence

    The National Academies says moderate drinkers live longer. Read that sentence slowly.

    The National Academies of Sciences, Engineering, and Medicine released today a congressionally requested review of moderate drinking — up to two drinks a day for men, one for women — and eight health outcomes.

    5 min read
  3. Evidence

    12.4 years: the number the longevity industry should be measured against

    Two Mayo Clinic researchers, Armin Garmany and Andre Terzic, published today in JAMA Network Open an analysis of World Health Organization data for 183 countries from 2000 to 2019, measuring the distance between how long people live and how long they live in good health.

    4 min read
  4. Psychology

    Oxford's word of the year is "brain rot." Longevity content is the premium tier.

    Oxford University Press named "brain rot" its Word of the Year today, after a public vote of more than 37,000 people. Oxford's definition: the supposed deterioration of a person's mental state from overconsuming trivial content, now particularly online.

    4 min read
  5. Access

    Ten Americas, a twenty-year gap, and the longevity industry's quietest problem

    The Lancet published "Ten Americas" today, an analysis by Laura Dwyer-Lindgren and colleagues at the Institute for Health Metrics and Evaluation that sorts the entire US population into ten groups by race, geography, income and related factors, and tracks their life expectancy from 2000 to 2021.

    4 min read
  6. Sleep

    The free hour: the only sleep gift the calendar gives you

    At 2 a.m. this morning, clocks in most of the United States went back an hour. For one night the country received the thing the longevity industry cannot sell: an extra hour of sleep, free, no device required.

    4 min read
  7. Follow the Money

    Two nonprofits merged today. Here is the part of longevity that does not scale.

    The SENS Research Foundation — a Mountain View nonprofit founded in 2009 around the idea that aging is accumulated damage that can be repaired — and Lifespan.io, a New York advocacy and crowdfunding group founded in 2014, announced today that they have completed a merger into a new…

    4 min read
  8. Movement

    Two days a week counted the same as seven. Read the fine print anyway.

    A study published today in Circulation followed nearly 90,000 UK Biobank participants who wore a wrist accelerometer for one week and were then tracked through their health records.

    4 min read
  9. Evidence

    A Blue Zones critic won an Ig Nobel today. What changes for you?

    The Blue Zones are five regions — Sardinia, Okinawa, Ikaria, Nicoya in Costa Rica and Loma Linda, California — reported to have unusual numbers of very old people, and one of the best-known stories about simple living and long life.

    4 min read